Lithium Carbonate

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Lithium Carbonate is the carbonate salt of lithium, a soft alkali metal, with antimanic and hematopoietic activities. Lithium interferes with transmembrane sodium exchange in nerve cells by affecting sodium, potassium-stimulated adenosine triphosphatase (Na+, K+-ATPase), alters the release of neurotransmitters, affects cyclic adenosine monophosphate (cAMP) concentrations, and blocks inositol metabolism resulting in depletion of cellular inositol and inhibition of phospholipase C-mediated signal transduction. The exact mechanism through which lithium exerts its mood-stabilizing effect has not been established. In addition, lithium stimulates granulocytopoiesis and appears to increase the level of pluripotent hematopoietic stem cells by stimulating the release of hematopoietic cytokines and/or directly acting on hematopoietic stem cells. Formula Li2CO3 Molar mass 73.888 g/mol CAS Number 554-13-2 Density 2.11 g/cm3 Purity/Grade ≥99.0% (ACS Reagent) Appearance Crystalline Water solubility 8.4 g/l at 20°C (68°F) – OECD Test Guideline 105 Melting point/freezing point 618°C (1


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