1-Bromopentane: Properties and Uses
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1-Bromopentane is an organic chemical compound related to the halides. The molecular formula of this substance is C5H11Br; the CAS number is 110-53-2. The chemical is known under different names, including pentyl bromide, n-amyl bromide, 1-pentylbromide, amyl bromide, etc.

Properties and Uses

1-Bromopentane is clear colorless to light yellow liquid characterized by the following properties:

  • Molecular weight: 151.04 g/mol;
  • Density: 1.218 g/mL;
  • Melting point: -95 °C;
  • Boiling point: 130 °C.

Pentyl bromide is insoluble in water, but soluble in alcohol and miscible with diethyl ether.

The chemical is mainly used in the organic synthesis reactions. It is also applied in iron-catalyzed alkylations of aromatic Grignard reagents via cross coupling, as well as in the synthesis of α, γ-diketo acids as reversible inhibitors of Hepatitis C virus.

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Storage and Safety

1-Bromopentane is a flammable chemical with a flash point 32 °C. It should be stored in a tightly closed container at room temperature away from sparks, fire, heat, and hot surfaces. Besides, the chemical is incompatible with strong bases and oxidizing agents.

Amyl bromide is harmful if swallowed and toxic to aquatic environment with long-lasting effect. When handling the substance, personal protective equipment:

  • eyeshields
  • face shields
  • gloves

is a must, since it can cause serious eye damage, skin and respiratory tract irritation.

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